Study shows CBD-A and CBG-A could prevent and treat COVID-19 infections
Hemp oil comes to save the day again, it seems. As researchers from Oregon in the United States prove that certain cannabinoids from cannabis could potentially prevent and treat coronavirus infections. The acidic forms of two immensely popular cannabinoids appear to block the dangerous virus from entering human cells. Helping to prevent COVID-19 infections and decrease the severity of symptoms when infected.
Hemp oil against coronavirus
While the whole world is currently in awe about the recent news that hemp might help prevent and treat coronavirus. We at DNH already wrote about the benefits of CBD oil in regards to COVID-19 back in november 2021, in our blog ‘Studies: 'CBD oil and Vitamin D3 could help treat and prevent COVID-19''.
But where those studies focus on the treatment of coronavirus or better yet, its consequences in the lungs. This new study ‘Cannabinoids Block Cellular Entry of SARS-CoV‐2 and the Emerging Variants’, published in the Journal of Natural Products, rather shows the way in which cannabinoids block the virus from entering human cells altogether. Not only helping to treat coronavirus when you’re infected; but actually preventing your body from getting infected with COVID-19 in the first place.
How cannabinoid acids prevent COVID-19 infection
As discovered by scientists from Oregon Health & Science University - lead by head researcher Richard van Breemen - two specific cannabinoid acids appear to be effective against various mutations of the novel coronavirus. Apparently, these non-decarboxylated cannabinoids bind to the protein-spikes of the virus. Consequently blocking an important weapon used by the SARS-virus to penetrate human cells and spread infection.
The two cannabinoid acids responsible for these effects are respectively Cannabidiolic-acid (CBD-A; as found in our CBD-A Oil) and Cannabigerol-acid (CBG-A). These are the acidic forms of two of the most popular cannabinoid products in our CBD webshop. Moreover, our well-balanced CBG oil actually contains both CBD-A and CBG-A! This means that the blend in this hemp oil might be an interesting asset in future coronavirus prevention and treatment.
CBDA and CBGA effective against various mutations
As quoted by Forbes Magazine, head researcher van Breemen said: ‘These cannabinoid acids are abundant in hemp and in many hemp extracts. They are not controlled substances like THC, the psychoactive ingredient in marijuana, and have a good safety profile in humans.’ While explaining that CBD-A and CBG-A 'showed equally effective against variants of SARS-CoV-2. Including variant B.1.1.7, which was first detected in the United Kingdom; and variant B.1.351, first detected in South Africa.'
By targeting the spike protein, these cannabinoid acids act much like current vaccines and SARS-CoV-2-antibody therapy do. But ‘orally bioavailable and with a long history or safe human use’, the researchers write. Contrary to these relatively new therapies pushed onto the pharmaceutical market at the moment.
‘Any part of the infection and replication cycle is a potential target for antiviral intervention, and the connection of the spike protein’s receptor binding domain to the human cell surface receptor ACE2 is a critical step in that cycle,’ according van Breemen. Who draws these conclusions following extensive in-vitro laboratory research with his skilled team.
Their findings suggest that so-called cell entry inhibitors, like the aforementioned acids from hemp, ‘could be used to prevent SARS-CoV-2 infection and also to shorten infections by preventing virus particles from infecting human cells.’ According to the research-team: ‘they bind to the spike proteins so those proteins can’t bind to the ACE2 enzyme. Which is abundant on the outer membrane of endothelial cells in the lungs and other organs.’ In other words, these cannabinoid acids protect the cells in our lungs and other organs from being penetrated - and thus infected - by the coronavirus-mutations.
CBG Oil as natural COVID-remedy?
Does this mean that our CBG oil treats coronavirus or prevents you from getting COVID-19? Who knows! At this point additional research is needed to understand exactly how treatment with hemp oil could help avoid covid-infections or decrease its symptoms. However, with this positive news about our beloved plant and its potential effects on this life-threatening virus, it probably doesn’t hurt to try.
(i)All information in these blogs is intended for educational purposes only and is in no way meant to replace medical advice. Do you have a serious condition? Please ask your physician for medical advice.