An explanation about the different types of CBD products on the market today.
There are various different types of CBD oil and formulas for sale on the market, all with different effects. There is a lot written and there are a lot of claims made, but little is known about the exact content and effects of the different products. Here is a closer look at the science and effects of the various different types of products.
CO2 extract (CBD paste)
A CO2 extract is, as the name indicates, a hemp concentrate, where CO2 has been used to extract the active ingredients from the plant material. In addition to the CBD, CO2 also extracts the fats, sugars, leaf green and other substances which don’t add anything if you purely want to extract the cannabinoids and terpenes. CO2 is often used in the food industry to produce extracts, as it literally extracts absolutely everything from the plant material.
A CBD CO2 extract contains approximately 1/3 of wax, which gives it a paste-like structure. Its thickness means a CO2 extract is usually offered in syringes. The bioavailability of a CO2 extract is approximately 6-12%, just like standard CBD oil. This means a mere 6 to 12% is going to be absorbed by the body. The amount of CBD present in a CO2 extract will depend on the type of fibre hemp used, the harvest time, the climate and the extractor’s knowledge.
CBD oils based on a CO2 extract(full plant product)
Most types of CBD oil available on the market have been made from a CO2 extract which has been diluted with oils such as olive oil, hemp seed oil or coconut oil. Hemp seed oil isn’t always as long-lasting and the disadvantage of coconut oil is that it can solidify, causing lumps. Coconut oil needs to be heated up before it can be taken. CBD oil is usually sold in a pipette bottle. The bioavailability is just like the hemp extract (CBD paste), 6-12%. As CBD oil is a diluted version of an extract, this will always contain less CBD compared to a pure extract.
CBD oil based on crystals
There are an increasing number of different types of CBD oil now being introduced to the market, which are based on CBD crystals. These crystals are either of natural or synthetic origin, with the difference between the two being indistinguishable. The natural crystals are isolated from fibre hemp and purified in such a way that a solid crystalline substance is formed.
There is nothing wrong with natural CBD crystals, they can be used safely. The synthetic CBD is made through various different chemical reactions, resulting in the plant’s biological synthesis being mimicked. The natural CBD and synthetic CBD are the exact same substance with the exact same effect. However, different compounds can be created during the production process of the synthetic CBD, which could prove harmful and can even cause unwanted side effects.
Residual chemicals from the chemical reaction will also remain in the synthetic CBD crystals. The biggest disadvantage of a CBD oil based on crystals is that it’s very difficult to distinguish between natural and synthetic CBD crystals. Synthetic crystals are virtually always sold as natural CBD crystals and oil makers can’t tell the difference without the intervention of a specialised laboratory. Another disadvantage of oil based on CBD crystals is that it purely contains CBD and is therefore missing a whole host of cannabinoids and terpenes, which means the medicinal effect will always be less than CBD oil which also includes all the cannabinoids and terpenes.
CBD oil at Nano Level
The next type of CBD oil is the CBD oil at nano level. CBD crystals or a hemp extract are brought to nano level using ultrasonic frequencies. Those selling this oil have stated the bioavailability is many times higher and this oil – according to the sellers – is therefore much more effectively absorbed by the body.
Effect of Nano CBD oil
Nano CBD is nothing more than CBD with a smaller particle size. Both CBD crystals and hemp extracts are used for the development of nano CBD. It’s like the molecule is reduced in size with the use of ultrasonic frequencies, but the CBD’s lipophilic properties remain the same. Even though Nano CBD is smaller and can therefore be absorbed by the body more easily, the body will still need to bind the Nano CBD to a lipoprotein. This results in a large part of the Nano CBD being broken down in the liver by enzymes. Nano CBD has been banned and there are also some major risks associated with this technique. For example, you don’t want to take hemp extract at nano level, as any heavy metals and pesticites present in the extract will also have been converted to nano parts and it goes without saying you don’t want these in your body. Nano CBD might be better absorbed by the body than the standard CBD oil, but it does have serious limitations. As is the case with the normal CBD oil and oil based on crystals, the nano CBD oil is also missing all the other active substances like other cannabinoids and terpenes. There are governmental limitations too, which are currently standing in the way of Nano CBD’s production and sales. The food authorities in EU have indicated that Nano CBD is NOVELL and banned and may not be sold on the market. The authorities have also indicated they will maintain this ban across all Nano supplements in general and therefore also the Nano CBD oil.
CBD oil based on Lecithin/ liposomes
An increasing number of CBD oils are now also being offered on the market based on lecithin. Lecithin is a so-called emulsifier agent and can therefore bind fats with water. Lecithin is very common in eggs, soy and sunflower seeds and is used, for example, to make mayonnaise. It has been stated that CBD formulas made with lecithin are more readily absorbed by the body as a result of the binding with lecithin. Comparisons are often made with so-called liposomal vitamin C formulas, where lecithin is also used to ensure the vitamin C is more effectively absorbed by the body. Lecithin makes sure fats can bind in the body, resulting in them being effectively broken down. At cell level lecithin is essential for a healthy cell function. Lecithin is definitely a healthy food supplement, but will it actually aid the absorption of CBD in the body too?
Effects of lecithin/liposomes with CBD
Lecithin can ensure fats bind with water, which we refer to as emulsion. Lecithin can therefore bind fatty substances such as CBD and mix them with water. However, the binding of CBD with lecithin is a very difficult process and the water solubility at room temperature is very low. Lecithin’s binding power is stronger than that of the body’s own lipoprotein, which means the CBD bound to the lecithin will be absorbed even less effectively than a standard CBD oil based on olive oil. In fact, as the lecithin ensures fats and fatty substances are strongly bound, lecithin is ideal for using as a natural cholesterol reducer and as a slimming agent. As the cannabinoids are also stored in tissue, lecithin can ensure the CBD is removed from the body at a faster pace. The lecithin binds to the CBD in the body and ensures this is expelled from the body faster via the urinary tract. You could therefore effectively use lecithin to, for example, remove THC from the system, but not to achieve better CBD or THC absorption, as lecithin’s powerful fat binding properties means it has a counterproductive effect on the absorption of lipophilic substances such as CBD and THC. On the other hand, lecithin can result in water soluble substances like vitamin C being absorbed by the body more effectively, resulting in a higher blood level, something which isn’t possible without the lecithin binding, with the exception of intravenous administration. This is referred to as a liposomal vitamin C solution. This therefore does work with water soluble vitamins, but not with lipophilic (fat soluble) substances like THC and CBD!
CBD based on BioACTIVE+ (CBDactive+)
A CBD oil based on BioACTIVE+ will be more effectively absorbed than the standard CBD oil, as the BioACTIVE+ contains a complex which acts like a transporter (lipoprotein) to the bloodstream, which means the CBD won’t first need to be bound to a lipoprotein by the body before it can end up in the bloodstream.
How does CBDactive+ work?
CBDactive+ was developed to increase CBD’s bioavailability and to make the CBD water soluble, ensuring CBDactive+ won’t just be absorbed more effectively, but will also have more application possibilities than the traditional oil-based CBD supplements. CBD is a lipid component and has to be metabolised by the body after ingestion, where the body has to bind the CBD to a lipoprotein (transporter) in order to get the CBD into the bloodstream. The body makes the CBD water-soluble itself – as a result of the binding to the bodies own lipoprotein. As the body is making the CBD water soluble itself, the CBD can be absorbed in the blood, which, of course, is made up of >90% water. As the body has to carry out a complicated metabolisation itself in order to make the CBD water soluble, almost 95% of the CBD is broken down by the liver during metabolisation and only approximately 5% will eventually reach the bloodstream. The body will have been able to make the 5% CBD which eventually does reach the bloodstream water-soluble itself by binding the CBD (lipid) to a lipoprotein.
CBDactive+ contains an advanced complex, which is bound to the CBD and acts like a lipoprotein (transporter) to the bloodstream. The bound CBD is therefore instantly water-soluble. As the CBD is already bound as a result of the BioACTIVE+ Formula in the supplement, the body won’t need to carry out a complicated metabolisation to get the CBD into the bloodstream. This means the body will actually absorb 99% of the bound CBD, based on the BioACTIVE+ Formula.
Another advantage of a CBD product based on the BioACTIVE+ Formula is that all terpenes naturally present in cannabis will result in a full entourage effect and will have some effect on the Cytochrome P450 enzyme system so the active ingredients will be broken down more slowly.
Another tip ...
Now you know a little more about the content and efficacy of various types of CBD oil available on the market today, it may well be easier to make the right choice when buying a CBD oil and choosing a CBD oil which meets your needs. Do bear in mind that not every oil seller will always have your best interests at heart and therefore always choose a supplier who knows what he’s talking about and has appropriate experience with cannabinoids. Also ask about the techniques used, the analyses and the ingredients, making sure you know it contains exactly what it says on the label.